Welcome to the Cell Polarity & Morphogenesis lab

April 15, 2016


Walther RF. Nunes De Almeida F., Vlassaks E., Burden JJ. & Pichaud F. Pak4 Is Required during Epithelial Polarity Remodeling through Regulating AJ Stability and Bazooka Retention at the ZA. 15; 45-53. Cell Reports , 15:–45-53 2016. PDF

Mencarelli C. & Pichaud F. Orthodenticle is required for the expression of principal recognition molecules that control axon targeting in the Drosophila retina. PLOS Genetics OPEN ACCESS: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005303

Pichaud F. Transcriptional regulation of tissue organization and cell morphogenesis: the fly retina as a case study. Dev. Biol., Available Online, Oct4, 2013. PDF

Pichaud F. Neuron survival; Say it with flowers.Curr Biol., 14(22), 1300-1309, 2013. PDF

Thompson BJ., Pichaud F. & Roper k. Sticking together the Crumbs - an unexpected function for an old friend. Nat. Rev. Mol. Cell., 14(3), 307-314, 2013. PDF

Robertson F., Pinal N., Fichelson P., & Pichaud F. Atonal and EGFR signalling orchestrate rok- and Drak-dependent adherens junction remodelling during ommatidia morphogenesis. Development, 139, 3432-3441, 2012. PDF

Fichelson P., Brigui A. & Pichaud F. Orthodenticle and Kruppel-homolog1 regulate Drosophila Photoreceptor Maturation. PNAS, vol. 109 no. 20 7893-7898, 2012. OPEN ACCESS: http://www.pnas.org/content/109/20/7893.full

Pinal N. & Pichaud F. Dynamin and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration. J. Cell Sci., 1564-70, 2011. PDF

Walther RF & Pichaud F. Crumbs/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling. Current Biology, 1–10, 2010. PDF

Richardson NC & Pichaud F. Crumbs is required to achieve proper organ size control during Drosophila head development. Development, 137, 641-650, 2010. PDF --------See "In this issue" comments--------

Genevet A, Polesello C, Blight K, Robertson F, Collinson LM, Pichaud F, Tapon N. The Hippo pathway regulates apical-domain size independently of its growth-control function. J Cell Sci. Jul 15;122 , 2009.

Hogan C, Dupré-Crochet S, Norman M, Kajita M, Zimmermann C, Pelling AE, Piddini E, Baena-López LA, Vincent JP, Itoh Y, Hosoya H, Pichaud F, Fujita Y. Characterization of the interface between normal and transformed epithelial cells. Nat Cell Biol. Apr;11(4):460-7, 2009.

Mazzoni EO, Celik A, Wernet MF, Vasiliauskas D, Johnston RJ, Cook TA, Pichaud F, Desplan C. Iroquois complex genes induce co-expression of rhodopsins in Drosophila. PLoS Biol. Apr 22, 2008. PDF

Corrigall D, Walther FR, Rodriguez L, Fichelson P & Pichaud F. Hh signalling is a principal inducer of Myosin II driven epithelial cell ingression in Drosophila. Dev. Cell, 13, 730–742, 2007. PDF Faculty of 1000 Biology: evaluations for Corrigall D et al Dev Cell 2007 Nov 13 (5) :730-42 http://www.f1000biology.com/article/id/1095991/evaluation

Bialucha CU, Ferber EC, Pichaud F, Peak-Chew SY, Fujita Y. p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase Czeta and regulates cell polarity. J Cell Biol., 4, 575-81, 2007. PDF

Sprecher S.G, Pichaud F & Desplan C. Adult & larval photoreceptors use different mechanisms to specify the same Rhodopsin fates. Genes & Dev., 21, 2182-95, 2007. PDF

Walther FR & Pichaud F. Immunofluorescent staining and imaging of the pupal and adult Drosophila visual system. Nature Protocol, 1, 2635 - 2642, 2007. PDF

Pinal N, Goberdhan D , Collinson L, Fujita Y, Cox I, Wilson C, Pichaud F. Regulated and polarized accumulation of PtdIns(3,4,5)P3 is essential for morphogenesis of the apical membrane in photoreceptor epithelial cells. Current Biology, 16, 140–149, 2006. PDF Faculty of 1000 Biology: evaluations for Pinal N et al Curr Biol 2006 Jan 24 16 (2) :140-9 http://www.f1000biology.com/article/id/1031003/evaluation

Leulier F, Ribeiro P , Palmer E, Tenev T, Takahashi K, Robertson D, Zachariou A, Pichaud F, Ueda R, Meier, P. Systematic In Vivo RNAi Analysis of Putative Components of the Drosophila Cell Death Machinery. Cell Death & Differentiation,00, 1-12, 2006. PDF

Wu S, Mehta S, Pichaud F, Bellen H, Quiocho F. The Sec15 protein, a component of the exocyst, contains a new all helix domain which interacts with a subset of Rab GTPases. Nature Structural & Molecular Biology,12(10):879-85, 2003. PDF

Wernet MF, Labhart T, Baumann F, Mazzoni EO, Pichaud F, Desplan C. Homothorax switches function of Drosophila photoreceptors from color to polarized light sensors. Cell, 115(3):267-79, 2003. PDF

Tahayato A, Sonneville R, Pichaud F, Wernet MF, Papatsenko D, Beaufils P, Cook T, Desplan C. Otd/Crx, a dual regulator for the specification of ommatidia subtypes in the Drosophila retina. Dev. Cell, 5(3):391-402, 2003. PDF Faculty of 1000 Biology: evaluations for Cook T et al Dev Cell 2003 Jun 4 (6) :853-64 http://www.f1000biology.com/article/id/1013862/evaluation

Cook T, Pichaud F, Sonneville R, Papatsenko D, Desplan C. Distinction between color photoreceptor cell fates is controlled by Prospero in Drosophila. Dev. Cell, 4(6):853-64, 2003. PDF

Bessa J, Gebelein B, Pichaud F, Casares F, Mann RS. Combinatorial control of Drosophila eye development by eyeless,homothorax, and teashirt. Genes Dev., 16(18):2415-27, 2002. PDF Faculty of 1000 Biology: evaluations for Bessa J et al Genes Dev 2002 Sep 15 16 (18) :2415-27 http://www.f1000biology.com/article/id/1009356/evaluation

Pichaud F, Desplan C. Pax genes and eye organogenesis. Curr Opin Genet Dev., 12(4):430-4, 2002. PDF

Pichaud F, Desplan C. Cell biology: a new view of photoreceptors. Nature, 416(6877):139-40, 2002. PDF

Pichaud F, Treisman J, Desplan C. Reinventing a common strategy for patterning the eye. Cell, 105(1):9-12, 2001. PDF

Pichaud F, Desplan C. A new visualization approach for identifying mutations that affect differentiation and organization of the Drosophila ommatidia. Development, 128(6):815-26, 2001. PDF

Pichaud F, Casares F. homothorax and iroquois-C genes are required for the establishment of territories within the developing eye disc. Mech of Dev., 96(1):15-25, 2000. PDF

Mollereau B, Wernet MF, Beaufils P, Killian D, Pichaud F, Kuhnlein R, Desplan C. A green fluorescent protein enhancer trap screen in Drosophila photoreceptor cells. Mech of Dev., 93(1-2):151-60, 2000.

Pichaud F, Briscoe A, Desplan C. Evolution of color vision. Curr Opin Neurobiol., 9(5):622-7, 1999. PDF

Frendo JL, Delage-Mourroux R, Cohen R, Pichaud F, Pidoux E, Guliana JM, Jullienne A. Calcitonin receptor mRNA expression in TT cells: effect of dexamethasone. Mol Cell Endocrinol., 139(1-2):37-43, 1998.

Pichaud F, Delage-Mourroux R, Frenkian M, Frendo JL, Roux S, de Vernejoul MC, Jullienne A. Type-I 15-hydroxyprostaglandin dehydrogenase: role in macrophage/osteoclast differentiation. Adv Exp Med Biol., 433:399-402, 1997.

Delage-Mourroux R, Frenkian M, Pichaud F, Frendo JL, Pidoux E, Jullienne A. Isoforms of type-I 15-hydroxyprostaglandin dehydrogenase mRNA. Adv Exp Med Biol., 433:391-4, 1997.

Frendo JL, Delage-Mourroux R, Cohen R, Pichaud F, Pidoux E, Guliana JM, Jullienne A.

Calcitonin receptor mRNA is expressed in human medullary thyroid carcinoma. Thyroid, 8(2):141-7, 1998.

Roux S, Pichaud F, Quinn J, Lalande A, Morieux C, Jullienne A, de Vernejoul MC. Effects of prostaglandins on human hematopoietic osteoclast precursors. Endocrinology, 138(4):1476-82, 1997.

Delage-Mourroux R, Pichaud F, Frendo JL, Pidoux E, Guliana JM, Moukhtar MS, Jullienne A.

Cloning and sequencing of a new 15-hydroxyprostaglandin dehydrogenase related mRNA. Gene, 188(1):143-8 1997.

Pichaud F, Roux S, Frendo JL, Delage-Mourroux R, Maclouf J, de Vernejoul MC, Moukhtar MS, Jullienne A. 1,25-dihydroxyvitamin D3 induces NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human neonatal monocytes. Blood, 89(6):2105-12, 1997.

Pichaud F, Delage-Mourroux R, Pidoux E, Jullienne A, Rousseau-Merck MF. Chromosomal localization of the type-I 15-PGDH gene to 4q34-q35. Hum Genet., 99(2):279-81, 1997.

Roux S, Quinn J, Pichaud F, Orcel P, Chastre E, Jullienne A, De Vernejoul MC. Human cord blood monocytes undergo terminal osteoclast differentiation in vitro in the presence of culture medium conditioned by giant cell tumor of bone. J Cell Physiol., 168(3):489-98, 1996.

Pichaud F, Frendo JL, Delage-Mourroux R, de Vernejoul MC, Moukhtar MS, Jullienne A. Sequence of a novel mRNA coding for a C-terminal-truncated form of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. Gene, 162(2):319-22, 1995.

Frendo JL, Pichaud F, Mourroux RD, Bouizar Z, Segond N, Moukhtar MS, Jullienne A. An isoform of the human calcitonin receptor is expressed in TT cells and in medullary carcinoma of the thyroid. FEBS Lett., 342(2):214-6, 1994.